CLINICAL AND EXPERIMENTAL RATIONALE FOR THE USE OF SODIUM CHLORIDE MINERAL WATER IN THE REHABILITATION OF PATIENTS WITH METABOLIC SYNDROME
DOI:
https://doi.org/10.36074/grail-of-science.20.03.2026.100Keywords:
metabolic syndrome, clinical trials, experimental model, sodium chloride mineral waters.Summary
The article presents the results of experimental and clinical studies of low-mineralized sodium chloride waters in white rats with a model of metabolic syndrome and patients with metabolic syndrome at the stage of restorative treatment. In laboratory animals with a model of metabolic syndrome, the use of the studied mineral waters led to an improvement in the indicators of carbohydrate and lipid metabolism, detoxification processes, restriction of weight gain, and restoration of behavioral reactions in the "open field" test. Patients in the main observation group were added to the restorative treatment complex with a course of balneotherapy in the form of drinking mineral water. Patients in the control group received a similar treatment complex with ordinary drinking water. According to a comparative assessment of the therapeutic effects obtained in both groups upon completion of the course of rehabilitation treatment, positive changes were identified, but to a greater extent in patients of the main group: a significant improvement in the coefficient of the “health index”, improvement of adaptive processes (according to general and biochemical blood tests), improvement in the quality of life according to the WAM questionnaire “well-being, activity, mood”. The results of the conducted clinical studies allow us to recommend adding to the basic treatment complex of patients with metabolic syndrome the course of internal use of low-mineralized sodium chloride mineral waters.
Downloads
Downloads
References
Qadrie, Z., Ashraf, H., Dar, M. A. (2025). METABOLIC SYNDROME: THE SILENT EPIDEMIC DRIVING mODERN HEALTH RISKS. International Journal of Alternative and Contemporary Therapy, 3(6), 1-8. https://medicaljournals.eu/index.php/IJACT/article/view/1924
Dobrowolski, P., Prejbisz, A., Kuryłowicz, A., Baska, A., Burchardt, P., et al. (2022). METABOLIC SYNDROME - A NEW DEFINITION AND MANAGEMENT GUIDELINES: A joint position paper by the Polish Society of Hypertension, Polish Society for the Treatment of Obesity, Polish Lipid Association, Polish Association for Study of Liver, Polish Society of Family Medicine, Polish Society of Lifestyle Medicine, Division of Prevention and Epidemiology Polish Cardiac Society, "Club 30" Polish Cardiac Society, and Division of Metabolic and Bariatric Surgery Society of Polish Surgeons. Arch Med Sci, 30, 18(5), 1133-1156. DOI: 10.5114/aoms/152921 DOI: https://doi.org/10.5114/aoms/152921
Tarcău, B. M., Vicaș, L. G., Filip, L., Maghiar, F., Șandor, M., et al. (2024).
EMERGING PERSPECTIVES ON THE SET OF CONDITIONS THAT LEAD TO THE EMERGENCE OF METABOLIC SYNDROME. J. Pers. Med, 14, 32. https://doi.org/10.3390/jpm14010032 DOI: https://doi.org/10.3390/jpm14010032
Hamooya, B. M., Siame, L. Muchaili, L., Masenga, S. K., Kirabo, A. (2025). METABOLIC SYNDROME: EPIDEMIOLOGY, MECHANISMS, AND CURRENT THERAPEUTIC APPROACHES. Front Nutr, Sep 3, 12, 1661603. DOI: 10.3389/fnut.2025.1661603 DOI: https://doi.org/10.3389/fnut.2025.1661603
Zheng, L., Zeng, A., Liu, L., Tian, W., Wang, R., et al. (2025). METABOLIC SYNDROME: MOLECULAR MECHANISMS AND THERAPEUTIC INTERVENTIONS. Mol Biomed, Aug 26, 6(1), 59. DOI: 10.1186/s43556-025-00303-5 DOI: https://doi.org/10.1186/s43556-025-00303-5
Narciso, L., Martinelli, A., Torriani, F., Frassantino, P., Bernardini, R., et al. (2022). NATURAL MINERAL WATERS AND METABOLIC SYNDROME: INSIGHTS FROM OBESE MALE AND FEMALE C57BL/6 MICE ON CALORIC RESTRICTION. Front Nutr, 9, 886078. https://doi.org/10.3389/fnut.2022.886078 DOI: https://doi.org/10.3389/fnut.2022.886078
Costa-Vieira, D., Monteiro, R., Martins, M. J. (2019). METABOLIC SYNDROME FEATURES: IS THERE A MODULATION ROLE BY MINERAL WATER CONSUMPTION? A REVIEW. Nutrient,. 11(5), 1141. https://doi.org/10.3390/nu11051141 DOI: https://doi.org/10.3390/nu11051141
Smirnov, I. V., Nasibullin, B. A., Gushcha, S. G., Plakida, A. L. (2024). INFLUENCE of mineral water with increased content of organic substances on MORPHIC-FUNCTIONAL INDICATORS OF THE BODY OF RATS WITH A MODEL OF METABOLIC SYNDROME. Odesa Medical Journal, 4(139), 19-24. DOI: 10.32782/2226-2008-2024-4-3 DOI: https://doi.org/10.32782/2226-2008-2024-4-3
Gunawan, S., Aulia, A., Soetikno, V. (2021). DEVELOPMENT OF RAT METABOLIC SYNDROME MODELS: A REVIEW. Vet World. 14(7), 1774-1783. DOI: 10.14202/vetworld.2021.1774-1783 DOI: https://doi.org/10.14202/vetworld.2021.1774-1783
Downloads
How to Cite
Issue
Section
Categories