CLINICAL AND EXPERIMENTAL RATIONALE FOR THE USE OF SODIUM CHLORIDE MINERAL WATER IN THE REHABILITATION OF PATIENTS WITH METABOLIC SYNDROME

CLINICAL AND EXPERIMENTAL RATIONALE FOR THE USE OF SODIUM CHLORIDE MINERAL WATER IN THE REHABILITATION OF PATIENTS WITH METABOLIC SYNDROME

Authors

  • Tatyana Polshchakova State Non-profit Enterprise «Ukrainian Research Institute of Rehabilitation and Resort Therapy of the Ministry of Нealth of Ukraine», Ukraine https://orcid.org/0000-0002-4403-6334
  • Iryna Zabolotna State Non-profit Enterprise «Ukrainian Research Institute of Rehabilitation and Resort Therapy of the Ministry of Нealth of Ukraine», Ukraine https://orcid.org/0000-0002-0159-2058
  • Iryna Balashova State Non-profit Enterprise «Ukrainian Research Institute of Rehabilitation and Resort Therapy of the Ministry of Health of Ukraine», Odesa National Medical University, Ukraine https://orcid.org/0000-0002-7529-4045
  • Sergеy Gushcha State Non-profit Enterprise «Ukrainian Research Institute of Rehabilitation and Resort Therapy of the Ministry of Нealth of Ukraine», Ukraine https://orcid.org/0000-0003-3097-5258

DOI:

https://doi.org/10.36074/grail-of-science.20.03.2026.100

Keywords:

metabolic syndrome, clinical trials, experimental model, sodium chloride mineral waters.

Summary

The article presents the results of experimental and clinical studies of low-mineralized sodium chloride waters in white rats with a model of metabolic syndrome and patients with metabolic syndrome at the stage of restorative treatment. In laboratory animals with a model of metabolic syndrome, the use of the studied mineral waters led to an improvement in the indicators of carbohydrate and lipid metabolism, detoxification processes, restriction of weight gain, and restoration of behavioral reactions in the "open field" test. Patients in the main observation group were added to the restorative treatment complex with a course of balneotherapy in the form of drinking mineral water. Patients in the control group received a similar treatment complex with ordinary drinking water. According to a comparative assessment of the therapeutic effects obtained in both groups upon completion of the course of rehabilitation treatment, positive changes were identified, but to a greater extent in patients of the main group: a significant improvement in the coefficient of the “health index”, improvement of adaptive processes (according to general and biochemical blood tests), improvement in the quality of life according to the WAM questionnaire “well-being, activity, mood”. The results of the conducted clinical studies allow us to recommend adding to the basic treatment complex of patients with metabolic syndrome the course of internal use of low-mineralized sodium chloride mineral waters.

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References

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Author Biographies

Tatyana Polshchakova, State Non-profit Enterprise «Ukrainian Research Institute of Rehabilitation and Resort Therapy of the Ministry of Нealth of Ukraine», Ukraine

Candidate of medical sciences, Senior Researcher, Leading Researcher of the Department Rehabilitation

Iryna Zabolotna, State Non-profit Enterprise «Ukrainian Research Institute of Rehabilitation and Resort Therapy of the Ministry of Нealth of Ukraine», Ukraine

Doctor of medical sciences, Senior Researcher, Head of the Department Rehabilitation from

Iryna Balashova, State Non-profit Enterprise «Ukrainian Research Institute of Rehabilitation and Resort Therapy of the Ministry of Health of Ukraine», Odesa National Medical University, Ukraine

Candidate of medical sciences, Senior Researcher Senior Researcher of Department Rehabilitation?

Docent of the Department of Internal Medicine No. 2 with postgraduate education

Sergеy Gushcha, State Non-profit Enterprise «Ukrainian Research Institute of Rehabilitation and Resort Therapy of the Ministry of Нealth of Ukraine», Ukraine

Сandidate of Medical Sciences, Senior Researcher, Head of the Experimental Research Department

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Published

23.03.2026

Number of views 148

How to Cite

Polshchakova, T., Zabolotna, I., Balashova, I., & Gushcha, S. . (2026). CLINICAL AND EXPERIMENTAL RATIONALE FOR THE USE OF SODIUM CHLORIDE MINERAL WATER IN THE REHABILITATION OF PATIENTS WITH METABOLIC SYNDROME. Grail of Science, (64), 858–863. https://doi.org/10.36074/grail-of-science.20.03.2026.100

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